This result was confirmed by indirect immunofluorescence assay (IFA) with HEp-2 cellCcoated slides (unpublished data). prior to the starting point of somatic hypermutation. We conclude a third checkpoint selects against self-reactivity during IgM+ storage B cell advancement in humans. Nearly … Continue reading This result was confirmed by indirect immunofluorescence assay (IFA) with HEp-2 cellCcoated slides (unpublished data)